RxODE: Facilities for Simulating from ODE-Based Models

Facilities for running simulations from ordinary differential equation ('ODE') models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The 'VODE' and 'LSODA' are in the public domain. The information is available in the inst/COPYRIGHTS.

Version: 1.1.5
Depends: R (≥ 4.0.0)
Imports: PreciseSums (≥ 0.3), Rcpp (≥ 0.12.3), assertthat, backports, checkmate, cli (≥ 2.0.0), dparser (≥ 0.1.8), ggplot2, inline, lotri (≥ 0.3.0), magrittr, memoise, methods, rex, qs, sys, tools, utils
LinkingTo: dparser (≥ 1.3.1-0), PreciseSums (≥ 0.3), RcppEigen (≥, RcppArmadillo (≥ 0.9.300.2.0), sitmo, StanHeaders (≥ 2.21.0), BH
Suggests: spelling, Matrix, DT, covr, crayon, curl, data.table (≥ 1.12.4), digest, dplyr (≥ 0.8.0), ggrepel, gridExtra, htmltools, knitr, learnr, microbenchmark, nlme, remotes, rlang, rmarkdown, scales, shiny, stringi, symengine, testthat, tidyr, usethis, vdiffr, xgxr, pillar, tibble, units (≥ 0.6-0), rsconnect, devtools, patchwork
Published: 2022-03-23
Author: Matthew L. Fidler ORCID iD [aut], Melissa Hallow [aut], Wenping Wang [aut, cre], Zufar Mulyukov [ctb], Alan Hindmarsh [ctb], Awad H. Al-Mohy [ctb], Matt Dowle [ctb], Cleve Moler [ctb], David Cooley [ctb], Drew Schmidt [ctb], Arun Srinivasan [ctb], Ernst Hairer [ctb], Gerhard Wanner [ctb], Goro Fuji [ctb], Hadley Wickham [ctb], Jack Dongarra [ctb], Linda Petzold [ctb], Martin Maechler [ctb], Matteo Fasiolo [ctb], Morwenn [ctb], Nicholas J. Higham [ctb], Roger B. Sidje [ctb], Simon Frost [ctb], Kevin Ushey [ctb], Yu Feng [ctb]
Maintainer: Wenping Wang <wwang8198 at gmail.com>
BugReports: https://github.com/nlmixrdevelopment/RxODE/issues/
License: GPL (≥ 3)
Copyright: see file COPYRIGHTS
URL: https://nlmixrdevelopment.github.io/RxODE/, https://github.com/nlmixrdevelopment/RxODE/
NeedsCompilation: yes
Language: en-US
Citation: RxODE citation info
Materials: README NEWS
In views: DifferentialEquations
CRAN checks: RxODE results


Reference manual: RxODE.pdf
Vignettes: RxODE ODE solving syntax


Package source: RxODE_1.1.5.tar.gz
Windows binaries: r-devel: RxODE_1.1.5.zip, r-release: RxODE_1.1.5.zip, r-oldrel: RxODE_1.1.5.zip
macOS binaries: r-release (arm64): RxODE_1.1.5.tgz, r-oldrel (arm64): RxODE_1.1.5.tgz, r-release (x86_64): RxODE_1.1.5.tgz, r-oldrel (x86_64): RxODE_1.1.5.tgz
Old sources: RxODE archive

Reverse dependencies:

Reverse imports: nlmixr
Reverse linking to: nlmixr
Reverse suggests: campsis, CGNM


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