Provides tools for assessing the shape of a dose-response curve by testing linearity and non-linearity at user-defined cut-offs. It also provides two methods of estimating a threshold dose, or the dose at which the dose-response function transitions to significantly increasing: bi-linear (based on pkg 'segmented') and smoothed with splines (based on pkg 'mgcv').

Documentation

Manual: drsmooth.pdf
Vignette: None available.

Maintainer: Anne Bichteler <abichteler at toxstrategies.com>

Author(s): Greg Hixon*, Chad Thompson*, Anne Bichteler*, Liz Abraham*

Install package and any missing dependencies by running this line in your R console:

install.packages("drsmooth")

Depends R (>= 3.0.1)
Imports boot, car, mgcv, multcomp, DTK, segmented, lubridate, pgirmess, stats
Suggests testthat
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Package drsmooth
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Version 1.9.0
Published 2015-09-25
License GPL (>= 3)
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NeedsCompilation no
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Package source drsmooth_1.9.0.tar.gz